No argument there...there's pros and cons to each platform. But IMO the more confined the environment, the more advantage the handgun has.
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The advantage of a handgun is that it can be carried on your person. A handgun with a suppressor is much more difficult to carry. So if I'm not going to carry a gun, and I have to go run and get a gun out of my safe if I need one at home, I'm going to get a long gun, not a handgun.
I think you can screw the suppressor on quick enough...just get a holster that has the little slot for the suppressor as well. I know I've seen 'em.
I modified one of my Safariland drop-leg holsters to accept the G17 with suppressor mounted. That being said, at night, the suppressed G17 is going to be fairly close at hand, and not in a holster. For close-confines, my first choice is the handgun, 2nd choice is an SBR, and 3rd choice is a shotgun.
You don't need to carry a holstered suppressed gun and you don't need to run and get anything.
I'm coming from the POV that it will be near my bedside and once it's in my hands, it won't be holstered.
There's nothing wrong with the suppressed pistol at that point.
Running downstairs in your skivvies to get a shotgun and finding a crook breaking into your safe is probably going to be the first of a long night's worth of troubles.