Since you stated you are color blind, at least partially then I don't know if I can help you much. I do use a green fiber optic rod on a .22lr pistol, a Buckmark and have not had any issue with it, other than it came loose. On two of my competition guns, shotguns, I run green fiber optic rods on them and have done so year around for over 8 years now, though I have broken a couple rods. I do have a little vial of several sizes and colors though I have only ever run the smallest green ones. Personally, I don't have an issue picking it up, though I am usually running colored shooting glasses and they do tint the background and are suppose to help make the target pop out for you to see. Now that said, the shooting I am doing I am not really using the fiber optic rod as an aiming point as much as a point of reference when mounting the gun. All I can tell you is try and see what works best for your eyes.
"I don't collect guns anymore, I stockpile weapons for ****ing war." Chuck P.
"Some days you eat the bacon, and other days the bacon eats you." SeriousStudent
"Don't complain when after killing scores of women and children in a mall, a group of well armed men who train to shoot people like you in the face show up to say hello." WillBrink
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