I looked into it for glaucoma since I have glaucoma in my right eye, but I couldn't find enough evidence it actually makes a difference to make me want to try it.
I looked into it for glaucoma since I have glaucoma in my right eye, but I couldn't find enough evidence it actually makes a difference to make me want to try it.
As CO has recreational MJ and FL does not, makes sense. It would be interesting to read up on how each state deals with med vs rec (of they have both) compared to those with med only. I'll have to look into that some more. At the moment, FL is the only one I'm tracking in terms of med use of MM.
- Will
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www.BrinkZone.com
LE/Mil specific info:
https://brinkzone.com/category/swatleomilitary/
“Those who do not view armed self defense as a basic human right, ignore the mass graves of those who died on their knees at the hands of tyrants.”
Yeah, it's pretty interesting to see the different approaches the various states have taken.
Personally, I give 0 shits if people use marijuana and I think that it should be 100% legal for everyone to use or not use as they see fit.
Having said that, however, I can't argue with Hmac's position on the subject...If I were a practicing MD and my livelihood depended upon keeping my DEA number, there is no way in hell I'd touch a MMJ applicant. Losing the ability to practice is, more or less, "doing harm" to your existing patients.
There are plenty of doctors who write MMJ papers, so it's not really a hardship if someone wants to get a card. My wife's Neuro guy offers all his patients a card as his standard of care, but that doesn't mean all MDs should be forced into that.
Last edited by kerplode; 04-18-18 at 17:58.
Interesting development. Pharma getting in on it (cuz they have no faith it works...) and FDA looks to pull CBD. And why? Because pharma filed INDs, not due to safety concerns nor efficacy per se by the FDA. Obviously CBD has been used before pharma ever existed.
https://www.nutraingredients-usa.com...dustry-meeting
And:
FDA Triggered Industry Shift From ‘CBD’ to ‘Hemp Extracts’ in Dietary Supplements
Amid the escalating demand for CBD in the United States, many companies are selling “hemp extracts,” a strategy based on regulatory and scientific considerations. Marketers of hemp extracts must distinguish their products from the compound (CBD) under investigation by GW Pharmaceuticals plc, which announced Thursday that an FDA committee unanimously recommended supporting approval of its new drug application for Epidiolex.
https://www.naturalproductsinsider.c...ry-supplements
- Will
General Performance/Fitness Advice for all
www.BrinkZone.com
LE/Mil specific info:
https://brinkzone.com/category/swatleomilitary/
“Those who do not view armed self defense as a basic human right, ignore the mass graves of those who died on their knees at the hands of tyrants.”
For those who suffer migraines, a combo of THC and CBD was more effective than commonly prescribed med for migraines, and slightly more effective for cluster headaches:
Marijuana Treats Migraine Pain Better Than Prescription Medication, Study Finds
In another win for marijuana research, a study has found that the active compounds in cannabis are more effective at reducing the frequency of acute migraine pain than prescription migraine meds, and with fewer side effects.
The study included a total of 127 participants who suffered from chronic migraines and cluster headaches, severe headaches that occur on one side of the head, often around an eye. Migraine pain usually affects both sides of the head and is often accompanied by light sensitivity and nausea.
The cannabis-based medication the researchers gave the participants was a combination of the two active compounds in marijuana: tetrahydrocannabinol (THC) and cannabidiol (CBD). THC is the psychoactive compound that gets pot users high; CBD doesn’t get you high, but research has shown that it provides therapeutic benefits, including relieving seizures in epileptic patients.
The study had two phases. In the first, sufferers of chronic, acute migraines were given varying doses of the THC-CBD drug. The results showed that those who received a 200mg dose each day for three months experienced significantly less pain--about 55% less (lower doses didn’t provide the same pain relief).
Cont:
https://www.forbes.com/sites/daviddi.../#59cbbadc3700
Source:
https://www.ean.org/amsterdam2017/3r...17.2844.0.html
See also:
Front Neurosci. 2018
Endocannabinoid System and Migraine Pain: An Update.
Abstract
The trigeminovascular system (TS) activation and the vasoactive release from trigeminal endings, in proximity of the meningeal vessels, are considered two of the main effector mechanisms of migraine attacks. Several other structures and mediators are involved, however, both upstream and alongside the TS. Among these, the endocannabinoid system (ES) has recently attracted considerable attention. Experimental and clinical data suggest indeed a link between dysregulation of this signaling complex and migraine headache. Clinical observations, in particular, show that the levels of anandamide (AEA)-one of the two primary endocannabinoid lipids-are reduced in cerebrospinal fluid and plasma of patients with chronic migraine (CM), and that this reduction is associated with pain facilitation in the spinal cord. AEA is produced on demand during inflammatory conditions and exerts most of its effects by acting on cannabinoid (CB) receptors. AEA is rapidly degraded by fatty acid amide hydrolase (FAAH) enzyme and its levels can be modulated in the peripheral and central nervous system (CNS) by FAAH inhibitors. Inhibition of AEA degradation via FAAH is a promising therapeutic target for migraine pain, since it is presumably associated to an increased availability of the endocannabinoid, specifically at the site where its formation is stimulated (e.g., trigeminal ganglion and/or meninges), thus prolonging its action.
https://www.ncbi.nlm.nih.gov/pubmed/29615860
- Will
General Performance/Fitness Advice for all
www.BrinkZone.com
LE/Mil specific info:
https://brinkzone.com/category/swatleomilitary/
“Those who do not view armed self defense as a basic human right, ignore the mass graves of those who died on their knees at the hands of tyrants.”
- Will
General Performance/Fitness Advice for all
www.BrinkZone.com
LE/Mil specific info:
https://brinkzone.com/category/swatleomilitary/
“Those who do not view armed self defense as a basic human right, ignore the mass graves of those who died on their knees at the hands of tyrants.”
Is CBD the next big find for athletes? Maybe, but far more data is needed. Interesting though:
Andrew Talansky is almost always sore. The 29-year-old spent seven years as a professional cyclist racing for Slipstream Sports. He recently switched to triathlon and now spends hours training both on and off the bike. “I’m using muscles I haven’t used in years,” Talansky says. “My body is constantly inflamed.” Many athletes in his situation rely on common pain relief like ibuprofen, but when Talansky strained a hip flexor last fall, he reached for a bottle of cannabidiol (CBD), an extract from the cannabis plant, instead.
“I took it for a couple of weeks, and there was a noticeable difference immediately,” Talansky says. “And it wasn’t just that my hip was feeling better. I was less anxious, and I was sleeping better.”
Marijuana has long been considered an alternative pain medication, with THC, the principle psychoactive compound in the plant, getting most of the attention. CBD is another active component and could offer some of the same medical benefits (anti-inflammatory, anti-anxiety, analgesic), but without the side effect of getting high. CBD interacts with serotonin and vanilloid receptors in the brain, which affect mood and the perception of pain. It also has antioxidant properties. The World Anti-Doping Agency (WADA) removed CBD from its list of banned substances in January, which prompted many professional athletes, including ultrarunner Avery Collins and mountain biker Teal Stetson-Lee, to eschew ibuprofen for CBD. Some believe it’s a safer alternative to drugstore pain relievers and anti-inflammatories.
https://www.outsideonline.com/229626...gn=onsiteshare
- Will
General Performance/Fitness Advice for all
www.BrinkZone.com
LE/Mil specific info:
https://brinkzone.com/category/swatleomilitary/
“Those who do not view armed self defense as a basic human right, ignore the mass graves of those who died on their knees at the hands of tyrants.”
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