Yes, that will happen. While I personally don't have any pistols with interchangeable backstraps, I shoot 1911s with a flat mainspring housing low, and so my 1911s have arched mainspring housings.
A friend with accuracy issues with his dept issued glock, vs his personal one turned out to be the larger backstrap on his issue gun.
Sent from my SGP612 using Tapatalk
Bookmarks