Penetration will likely be far better with the 308 FMJ. You will certainly hit the target with more energy and a better sectional density.
A .223 soft point, like the 64gr Powerpoints, are a known good performer on deer sized game in states that allow such calibers to be used in big game hunting. I understand that 5.56 will kill pigs pretty cleanly too, if you know WTF you are doing.
To make a valid comparison, in my mind, you have to remove variables not introduce them in a "handicapped match-up".
I like shooting big game with 168gr Barnes TSX in 308Win. I wouldn't hesitate to use 75gr TAP on two-legged varmints, either.
"I'm not saying I invented the turtleneck. But I was the first person to realize its potential as a tactical garment. The tactical turtleneck! The... tactleneck! - Sterling Archer"
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"Courage is not the absence of fear, but rather the judgment that something else is more important
than one's fear. The timid presume it is lack of fear that allows the brave to act when the timid do not."
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