I have been shooting 22's all my life. I recently purchased a 15-22. I have tweaked the sights on my AR-15 per the instructions on the sticky for found in the general AR thread on sight adjustments. The 15-22 has the exact same sights. Generally I sight in iron sights for a 22 @ 50 yards. (Best my 53 year old eyes can cope with). Using 50 yards as my base (is another base better?), how should I set the sights? How can I get the best utility out of this caliber and these sights?

THANKS!!!