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You are going to have to cross wide open spaces, forested areas, semi-urban, and heavily urban areas. If you have a family, take that into consideration.
The S*** Has Hit The Fan(for whatever reason) and you have to get to coordinates that require you to(eventually) cross all these types of terrain. The general population must be considered potentially dangerous because they may want what you have.
You will have to spend nights in areas ranging from the forest to urban. Any and all situations have the potential to arise. You may stay in a barn one night, an apartment building in the city the next, and in a forest the next. Potentially deadly confrontations may occur in any one of these locations.
That's a damn near impossible scenario for anybody short of a well-prepared group or a highly-skilled lone wolf tracker type.