Another point to consider is that the .300 will reduce mag capacity to 3 rounds instead of 5 for a standard bolt face cartridge...if that matters. The .300 will cost a lot more to shoot and will wear the barrel a lot faster than one of the standard (take your pick) cartridges such as .308, 7-08, .30-06, .270 etc.
The .300 is a great cartridge for long range shooting, but the rifles usually have heavy barrels and stocks, along with high magnification optics.
The .308 shines because of the availability of excellent and accurate factory loads and rifles. Other notable characteristics include its accuracy, its long barrel life and the fact that it has enough power to use for any game in the lower 48. It comes close to the mythical "do it all" type of cartridge.
As for which rifle...a Remy or a Winchester, I favor the Model 70 for its design characteristics...flat bottom, integral recoil lug, field strippable bolt, etc.
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