I read the research when it came out and it's interesting and confirms what anyone who has trained enough people/been involved in enough research already knows: genetics rules all.
No matter what form of exercise you expose people to, you will have a small % of non responders, a bunch of "average" responders, and a small % of super responders, hence the bell curve/data plots one can see on any study.
No one knew exactly why that was the case, but genetic differences as well as possible confounders not accounted for, was generally assume the reason.
That they have found the specific genes that tell us who may respond well and who wont to aerobics is a start of such genetic tests that will allow people to tailor an exercise plan that allows them to maximize their genetic potential. However, it also opens a lot of questions and added complications that don't account for other variables in the equation.
Brave new world to be sure, and some really interesting genetic related tests, etc will be the norm shortly!
Are You Likely to Respond to Exercise?
Research has confirmed that people’s physiological responses to exercise vary wildly. Now a new genetic test promises to tell you whether you are likely to benefit aerobically from exercise. The science behind the test is promising, but is this information any of us really needs to know?
The new test, which is being sold by a British company called XRGenomics, is available to anyone through the company’s Web site and involves rubbing inside your cheek with a supplied swab and returning the tissue sample to the company. Results are then available within a few weeks. It is based on a body of research led by James Timmons, a professor of systems biology at Loughborough University in England, and colleagues at the Pennington Biomedical Research Center in Louisiana and other institutions.
That original research, published in a landmark 2010 study, looked into the genetics of why some people respond to endurance exercise so robustly, while others do not. Some lucky men and women take up jogging, for example, and quickly become much more aerobically fit. Others complete the same program and develop little if any additional endurance, as measured by increases in their VO12 max, or their body’s ability to consume and distribute oxygen to laboring muscles.
For the 2010 study, Dr. Timmons and his colleagues genotyped muscle tissue from several groups of volunteers who had completed 6 to 20 weeks of endurance training. They found that about 30 variations in how genes were expressed had a significant effect on how fit people became. The new test looks for those genetic markers in people’s DNA.
CONT:
http://well.blogs.nytimes.com/2012/1...cise/?src=recg
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Originally Posted by Heavy Metal
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