Another "T Boosters" Bites The Dust (D-ASP study)

[WillBrink]

I'm not surprised there was no effects on body comp (compared to placebo) but I am a little surprised it had no stat sig effects on serum hormones tested. Regardless, falls where all "T boosters" fall for me via this prior article on T boosters*

d-Aspartic acid supplementation combined with 28 days of heavy resistance training has no effect on body composition, muscle strength, and serum hormones associated with the hypothalamo-pituitary-gonadal axis in resistance-trained men

Department of Health, Exercise and Biochemical Nutrition Lab, Human Performance, and Recreation, Baylor University, Waco, TX, USA

Abstract

It was hypothesized that d-aspartic acid (D-ASP) supplementation would not increase endogenous testosterone levels or improve muscular performance associated with resistance training. Therefore, body composition, muscle strength, and serum hormone levels associated with the hypothalamo-pituitary-gonadal axis were studied after 28 days of resistance training and D-ASP supplementation. Resistance-trained men resistance trained 4 times/wk for 28 days while orally ingesting either 3 g of placebo or 3 g of D-ASP.

Data were analyzed with 2 × 2 analysis of variance (P < .05). Before and after resistance training and supplementation, body composition and muscle strength, serum gonadal hormones, and serum D-ASP and d-aspartate oxidase (DDO) were determined. Body composition and muscle strength were significantly increased in both groups in response to resistance training (P < .05) but not different from one another (P > .05). Total and free testosterone, luteinizing hormone, gonadotropin-releasing hormone, and estradiol were unchanged with resistance training and D-ASP supplementation (P > .05).

For serum D-ASP and DDO, D-ASP resulted in a slight increase compared with baseline levels (P > .05). For the D-ASP group, the levels of serum DDO were significantly increased compared with placebo (P < .05). The gonadal hormones were unaffected by 28 days of D-ASP supplementation and not associated with the observed increases in muscle strength and mass.

Therefore, at the dose provided, D-ASP supplementation is ineffective in up-regulating the activity of the hypothalamo-pituitary-gonadal axis and has no anabolic or ergogenic effects in skeletal muscle.

* = Finally, the FACTS about Testosterone Boosting Supplements!

Source: d-Aspartic acid supplementation combined with 28 days of heavy resistance training has no effect on body composition, muscle strength, and serum hormones associated with the hypothalamo-pituitary-gonadal axis in resistance-trained men

[onado2000]

In terms of boosting T production, does Clomid boost testosterone production ? Sorry off track from original topic/study, but would like to pick your brain in regard to clomid. Thanks

[WillBrink]

In terms of boosting T production, does Clomid boost testosterone production ? Sorry off track from original topic/study, but would like to pick your brain in regard to clomid. Thanks

It does appear to yes. That does not mean it would be recommended for that use/as TRT however.

[Doc Safari]

Thanks for posting this. Over the years I've come to the conclusion that Tribulus Terrestris and Fenugreek have a mild effect (all I was looking for), but DAA was a new supplement that I've been trying. Frankly I couldn't see much comparison between it and Fenugreek or Tribulus.

[WillBrink]

Thanks for posting this. Over the years I've come to the conclusion that Tribulus Terrestris and Fenugreek have a mild effect (all I was looking for), but DAA was a new supplement that I've been trying. Frankly I couldn't see much comparison between it and Fenugreek or Tribulus.

If interested in my general take on the "T booster" category in general, see linked article above. I don't have any faith in any of them at this time for reasons outlined.

[Doc Safari]

If interested in my general take on the "T booster" category in general, see linked article above. I don't have any faith in any of them at this time for reasons outlined.

Yes, I know that in general you don't think any of them work. I don't have any scientific evidence, but having taken several different ones I can see a definite, if unspectacular, effect in some supplements over others. For example, Chrysin may as well be sugar pills, but Fenugreek definitely seems to increase energy, libido, etc., in a minor way.

[WillBrink]

Yes, I know that in general you don't think any of them work. I don't have any scientific evidence, but having taken several different ones I can see a definite, if unspectacular, effect in some supplements over others. For example, Chrysin may as well be sugar pills, but Fenugreek definitely seems to increase energy, libido, etc., in a minor way.

There's scant data on Fenugreek and T levels, but it appears to have other health related benefits at least. So, all good.

[Doc Safari]

There's scant data on Fenugreek and T levels, but it appears to have other health related benefits at least. So, all good.

I realize that you try to maintain strict scientific standards and my evidence is all anecdotal, but I have enough experience to know some things work and some don't.

For example, I don't want to get too graphic but I took a Tribulus a couple of hours ago and I'm sitting here at the desk with wood.

I also feel more energized and ready to take on anything.

I guess I use it more as my version of "Five-Hour Energy" than anything, but the stuff does have an effect.

I'd call it giving my 'nads their own little cup of coffee.

[WillBrink]

I realize that you try to maintain strict scientific standards and my evidence is all anecdotal, but I have enough experience to know some things work and some don't.

For example, I don't want to get too graphic but I took a Tribulus a couple of hours ago and I'm sitting here at the desk with wood.

I also feel more energized and ready to take on anything.

I guess I use it more as my version of "Five-Hour Energy" than anything, but the stuff does have an effect.

I'd call it giving my 'nads their own little cup of coffee.

Too much sharing bro! :

[Vic303]

Fenugreek has two well known and documented effects...neither of which apply
to or benefit 99% of folks on this site...