To Arctic 1:
While I agree "total exsanguination" is not super likely, as stated above, you don't need to lose all of it to die. Shock is a metabolic state; start hypoperfusion of small capillary beds, start making free radicals and ultimately cell death, and you start having problems. Even if you rapidly fluid resuscitate, you can get a second-hit/reperfusion type effect and continue with organ death. This is one reason why rapid isotonic fluid boluses are starting to be supplemented w/ colloids and blood products (and ATLS reflects this) - no use replacing volume with salt water.
Not to mention coagulation defects and delayed DIC, hypothermia as part of the triad, etc. And in older folks, you have to worry about already compromised organ systems; I've heard of people having fatal MI's while having orthostatic vitals taken (I assume that counts as "Positive").
Concur, and I never stated otherwise. I am not implying that casualties with femoral injuries will walk it off.
As for cardiac output is cardiac output ... well, CO= SV x HR. Tachycardia can make up for the decrease in SV as your total volume drops. In a healthy athlete, I'm sure it's entirely possible for the heart to be pumping more than entire volume per minute (70ml x 150 bpm = 10,500). As I said in my OP, the numbers were rounded for easy math.
I understand the point you were trying to make, I just thought it was odd that you would list total blood volume as approx. 5 liters, and then use numbers that listed cardiac output as 3 liters for a person at rest. If I did not know better it could be confusing.
Out of curiosity, have you done pig labs personally? Yes, arteries tend to spasm and slow blood flow. Ultimately though, they relax. In addition, ragged edges decrease the effectiveness of this mechanism. This can buy time, but I'm absolutely certain there are ways to exsanguinate in 5 minutes (complete transection of the femoral A., ruputured aorta, etc)
I have not done pig labs that are focused on blood loss personally, no. That does not invalidate the data, and the data shows that even with complete femoral transections, survival rates can be high, even 100%.
Still, I did not intend to imply that this vid depicts how all upper thigh GSW's with femoral injuries will play out; it is a real situation that depicts a possible scenario for aid providers.
And aortic ruptures aren't really comparable to the type of bleeding we are discussing here, as mortality rates are incredibly high, for a number of reasons. But I'll concede that a person will die from a ruptured aorta pretty quickly
Some interesting abstracts:
http://www.ncbi.nlm.nih.gov/pubmed/21514772
http://www.ncbi.nlm.nih.gov/pubmed/23816260 (appears most of deaths were not acute, based on other cited sources)
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