A pill that will make your dog - and maybe you - live longer?

[WillBrink]

The answer appears to be yes. Rapamycin has extensive data with animals and now being used in the "real world" with dogs. Work in humans? Very likely the answer is yes, and there are people using it, but it's NOT something you buy and just starting using as it's also toxic at high doses and used to suppress the immune system for those with organ transplants. So, look into it for your dogs and keep an eye out for coming human studies, and clinical experiences. More to come on rapamycin shortly.

"It's been remarkable," Paola Anderson said as she watched Momo, her 13-year-old white Pomsky, run around the backyard, keeping up with dogs a third his age. The drug is called rapamycin. After nearly a decade of research showing that it makes mice live up to 60% longer, scientists are trying it out as an anti-aging drug in dogs and humans."

http://www.cnn.com/2016/10/06/health...ger/index.html

See also:

http://veterinarynews.dvm360.com/rap...fountain-youth

[kerplode]

This will put a hurtin' on the gold digging industry...Be a lot harder to ride some old oil baron until his ticker explodes when he's all hopped up on Rapamycin! ;-)

For me, though, pretty much the last thing I'm interested in is living 60% longer. F*ck that noise. I'll do my 60yrs or whatever and call it good. I can't imagine what an unmitigated shithole this planet will be by 2105 or whenever.

[WillBrink]

This will put a hurtin' on the gold digging industry...Be a lot harder to ride some old oil baron until his ticker explodes when he's all hopped up on Rapamycin! ;-)

For me, though, pretty much the last thing I'm interested in is living 60% longer. F*ck that noise. I'll do my 60yrs or whatever and call it good. I can't imagine what an unmitigated shithole this planet will be by 2105 or whenever.

I plan to live long enough to have my consciousness transferred into a combat sex bot post singularity. I'm semi srs...but Rapamycin, along with some other evolving treatments, more likely to put quality life to your years than years to your life, followed shortly by treatments that will genuinely add both. I just returned from conference that explored the cutting edge of anti aging/longevity science on all fronts. Some very exciting stuff coming shortly. Age gracefully? Fu&^ that.

[kerplode]

Cool, man...Enjoy the wasteland that will be the future of this planet.

[WillBrink]

Cool, man...Enjoy the wasteland that will be the future of this planet.

Or maybe I'm on another planet....

[kerplode]

:-) There you go...I can dig it!

Actually that sounds alright. Martian combat sex bot for the win!

K...You convinced me.

[Co-gnARR]

Or maybe I'm on another planet....

Now that's the spirit!

In all seriousness, is there any info on the mechanism(s) in which this works? Does it
affect the mitochondrial functions, protect telomeres from unraveling, etc?
Did not read the linked article since I am at work....

[Lefty223]

... more likely to put quality life to your years than years to your life, followed shortly by treatments that will genuinely add both.

Well stated ...

FWIW I've reading quite a bit lately about the effects of the 'oxidation' process on the body as we age, and/or diseases like Alzheimers, mostly articles from super foodies. But the evidence does show the benefits of the Mediterranean diet and while I forget the compound, a food like spinach sauted in olive oil releases or promotes the compound that staves off or fights the free radicals that advance the disease ... and aging process.

To me, the thought about 'oxidation' being at the root of many of the aging issues is a neat concept. We can all think of items used in our daily lives that age and deterioate due to oxidizing ... dull paint on an old car left in the sun, old pieces of elastomers or rubber that are no longer pliable or useful and no longer seal, etc.

[WillBrink]

Well stated ...

FWIW I've reading quite a bit lately about the effects of the 'oxidation' process on the body as we age, and/or diseases like Alzheimers, mostly articles from super foodies. But the evidence does show the benefits of the Mediterranean diet and while I forget the compound, a food like spinach sauted in olive oil releases or promotes the compound that staves off or fights the free radicals that advance the disease ... and aging process.

To me, the thought about 'oxidation' being at the root of many of the aging issues is a neat concept. We can all think of items used in our daily lives that age and deterioate due to oxidizing ... dull paint on an old car left in the sun, old pieces of elastomers or rubber that are no longer pliable or useful and no longer seal, etc.

Free radicals are part of the aging process, but it's also not something we can live without, so while controlling oxidation by free radicals via anti oxidants is important, it's not the key to aging and an out dated model of aging as the primary cause it was once viewed.

[WillBrink]

Instead starting a new thread, gonna post this here as it does pertain sorta to the OP:

Just posted my write up of this anti aging/longevity conference I attended:


Aging and dying sucks. That should be the motto of RAADFest, the conference that explores the very cutting edge of anti aging/longevity research and therapies. I, being a politically incorrect jerk, would used that motto, because it’s true, but the RAADFest organizers have chosen the motto “Take your place in the revolution against aging and death” which is more descriptive than my motto I suppose. The goal of RAADFest is to explore “radical” life extension via the latest technologies as well as look at emerging and future technologies. This goes way past things like good nutrition, supplements and exercise, all of which can help slow aging and prevent the diseases of aging, none will stop it.

The ultimate goal of RAADFest and its speakers and attendees, is to put an end to aging and death, and that may in fact be a reality sooner than many realize. The overall tone of RAADFest being one of “transhumanism” which is “the belief or theory that the human race can evolve beyond its current physical and mental limitations, especially by means of science and technology.” Assuming we don’t snuff ourselves out as a species in the coming decades due to being short sighted and small minded, the transhumanism movement will be science fact vs. fiction according to many scientists. I tend to agree.

Cont:

http://www.brinkzone.com/articles/ra...nference-2017/