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Thread: Covid 19: adjuvant approaches etc,

  1. #141
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    While it has its limitations to be sure, still a study of major importance here. It’s odd they mention whey in the context of its impact on GSH in one short sentence, and clearly miss the importance of that as it applies to their results, but a very important study:

    Effect of Whey Proteins on Malnutrition and Extubating Time of Critically Ill COVID-19 Patients
    Abstract


    The novel SARS-CoV-2 virus has led to a severe pandemic, starting from early 2020. Intensive care (ICU) management of the COVID-19 disease is difficult with high morbidity and mortality. Early nutritional support, especially with whey protein, seems to be crucial in this medical case. Thus, we aimed to assess the effects of an adequate nutritional protocol rich in whey protein on nutritional and inflammatory status, extubating time, and mortality of critically ill COVID-19 patients (CICP). Methods: A prospective single-center exploratory observational study was undertaken on 32 consecutive CICP admitted to the ICU of Santa Maria Hospital, Terni, Italy, and treated with whey protein-enriched formula. Patients’ demographics, nutritional status, indexes of inflammation, daily pre-albumin serum levels, duration of mechanical ventilation, and mortality were recorded.

    Results: Thirty-two patients were enrolled. Ninety-five percent of them showed a gradual reduction in C-reactive protein (CRP) values and increase in pre-albumin levels after the whey protein-enriched formula. Prealbumin levels were not correlated with a better nutritional status but with a shorter extubating time and better survival. Conclusions: An adequate administration of whey protein during COVID-19 patients’ ICU stays can provide fast achievement of protein targets, reducing the duration of mechanical ventilation, and improving inflammatory status and ICU survival.

    Full paper:

    https://www.mdpi.com/2072-6643/14/3/437/htm
    Last edited by WillBrink; 01-20-22 at 13:44.
    - Will

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  2. #142
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    Ivermectin given if you spike a temp after an exposure.... it works , it's not a miracle drug but could have saved lives, what they did is criminal... it will all come out.
    --------
    Conclusions:
    Moderate-certainty evidence finds that large reductions in COVID-19 deaths are possible using ivermectin
    ‐---------
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8248252/

  3. #143
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    Quote Originally Posted by Backfire View Post
    Ivermectin given if you spike a temp after an exposure.... it works , it's not a miracle drug but could have saved lives, what they did is criminal... it will all come out.
    --------
    Conclusions:
    Moderate-certainty evidence finds that large reductions in COVID-19 deaths are possible using ivermectin
    ‐---------
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8248252/
    I'm still in the "might be worth using along with other modalities" camp as data is mixed at best. Just published, largest best controlled study to date, didn't find benefits:

    https://jamanetwork.com/journals/jam...rticle/2789362
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  4. #144
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    Jama is corrupted. Just like the medical community, they go against the narritive they get threatened. Same as any MD on YT walks a fine line.
    Hear it from the docs themselves
    https://rumble.com/vtamrn-covid-19-a...ght-video.html

    Certainly not a miracle drug, but can save lives if given at the right time.

    Fauci is the big dog, you must follow the narritive if you want any funding, if you think docs were able to treat as they saw fit, watch the video, they had to follow the death protocol

  5. #145
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    Even DARPA states that it is curative
    https://cdn.substack.com/image/fetch...2048x1156.jpeg

  6. #146
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    Quote Originally Posted by Backfire View Post
    Jama is corrupted. Just like the medical community, they go against the narritive they get threatened. Same as any MD on YT walks a fine line.
    Hear it from the docs themselves
    https://rumble.com/vtamrn-covid-19-a...ght-video.html

    Certainly not a miracle drug, but can save lives if given at the right time.

    Fauci is the big dog, you must follow the narritive if you want any funding, if you think docs were able to treat as they saw fit, watch the video, they had to follow the death protocol
    I'm well aware of those docs, followed it and them since the start, and not going to debate the topic here, as it's been discussed at length in prior threads. The vid covers various approaches, not just IVM, and they all continue to miss the key aspects of what drives the serious complications and death from vid, as covered in the OP linked article, as well as the best review on IVM.

    The way the main stream approached covid was as bad as it is for many others, that kill far more people, which I have been discussing 30+ years now, so welcome to my world...
    - Will

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    “Those who do not view armed self defense as a basic human right, ignore the mass graves of those who died on their knees at the hands of tyrants.”

  7. #147
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    Good review paper on what I have been stressing that mechanism since the beginning (1), largely overlooked and not addressed during the pandemic:

    The Role of Glutathione in Protecting against the Severe Inflammatory Response Triggered by COVID-19

    Abstract

    The novel COVID-19 pandemic is affecting the world’s population differently: mostly in the presence of conditions such as aging, diabetes and hypertension the virus triggers a lethal cytokine storm and patients die from acute respiratory distress syndrome, whereas in many cases the disease has a mild or even asymptomatic progression. A common denominator in all conditions associated with COVID-19 appears to be the impaired redox homeostasis responsible for reactive oxygen species (ROS) accumulation; therefore, levels of glutathione (GSH), the key anti-oxidant guardian in all tissues, could be critical in extinguishing the exacerbated inflammation that triggers organ failure in COVID-19. The present review provides a biochemical investigation of the mechanisms leading to deadly inflammation in severe COVID-19, counterbalanced by GSH. The pathways competing for GSH are described to illustrate the events concurring to cause a depletion of endogenous GSH stocks. Drawing on evidence from literature that demonstrates the reduced levels of GSH in the main conditions clinically associated with severe disease, we highlight the relevance of restoring GSH levels in the attempt to protect the most vulnerable subjects from severe symptoms of COVID-19. Finally, we discuss the current data about the feasibility of increasing GSH levels, which could be used to prevent and subdue the disease.

    Full paper:

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7402141/

    (1) Recently updated with additional sources, etc: https://brinkzone.com/life-saving-st...complications/
    - Will

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  8. #148
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    Melatonin and Long Covid 😷

    Melatonin was identified a while ago as a possible benefit to Covid, but it may also be valuable to those dealing with long Covid:

    "Studies have shown that in more than 30% of cases, secondary neurological symptoms, including headache, anosmia, myalgia, hemorrhage, seizure, and stroke, persist for a long period of time. This condition is defined as “long COVID”.

    In the current study, the scientists have investigated whether melatonin and melatonin-derived medicines can prevent the brain entry of SARS-CoV-2 in human angiotensin converting enzyme 2 (ACE2)-expressing mice."

    https://www.news-medical.net/news/20...ce-brains.aspx

    Study: https://www.biorxiv.org/content/10.1...12.30.474561v1
    - Will

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    “Those who do not view armed self defense as a basic human right, ignore the mass graves of those who died on their knees at the hands of tyrants.”

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