Covid 19: adjuvant approaches etc,

[WillBrink]

Correlational but the finding has been robust and consistent:

Vitamin D deficiency on admission to hospital was associated with a 3.7-fold increase in the odds of dying from COVID-19, according to an observational study looking back at data from the first wave of the pandemic.

Nearly 60% of patients with COVID-19 were vitamin D deficient upon hospitalization, with men in the advanced stages of COVID-19 pneumonia showing the greatest deficit.
Importantly, the results were independent of comorbidities known to be affected by vitamin D deficiency, say the authors, led by Dieter De Smet, MD, from AZ Delta General Hospital, Roeselare, Belgium.

"[The findings] highlight the need for randomized controlled trials specifically targeting vitamin D–deficient patients at intake, and make a call for general avoidance of vitamin D deficiency as a safe and inexpensive possible mitigation of the SARS-CoV-2 pandemic," say De Smet and colleagues in their article, published online November 25 in the American Journal of Clinical Pathology.

https://www.medscape.com/viewarticle/942497

Study:

https://academic.oup.com/ajcp/advanc...qaa252/6000689

[Arik]

Can anyone confirm this one way or another?

https://www.independentsentinel.com/...unnecessarily/

"The American Medical Association has officially rescinded a previous statement against the use of Hydroxychloroquine (HCQ) in the treatment of COVID-19 patients. Physicians can use it at their discretion.


In March, the AMA had issued a statement that was highly critical of HCQ in regards to its use as a proposed treatment by some physicians in the early stages of COVID-19.

The AMA discouraged doctors from ordering the medication in bulk for “off-label” use. They use it for illnesses like malaria and rheumatoid arthritis.

The AMA also claimed that there was no proof that it was effective in treating COVID. They added it could be harmful in some instances.

As it happens, on page 18 of a recent AMA memo, issued on October 30 (resolution 509, page 3), the organization officially reversed its stance on HCQ. Now, they say its potential for good currently may supersede the threat of any potentially harmful side effects"



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[WillBrink]

Can anyone confirm this one way or another?

https://www.independentsentinel.com/...unnecessarily/

"The American Medical Association has officially rescinded a previous statement against the use of Hydroxychloroquine (HCQ) in the treatment of COVID-19 patients. Physicians can use it at their discretion.


In March, the AMA had issued a statement that was highly critical of HCQ in regards to its use as a proposed treatment by some physicians in the early stages of COVID-19.

The AMA discouraged doctors from ordering the medication in bulk for “off-label” use. They use it for illnesses like malaria and rheumatoid arthritis.

The AMA also claimed that there was no proof that it was effective in treating COVID. They added it could be harmful in some instances.

As it happens, on page 18 of a recent AMA memo, issued on October 30 (resolution 509, page 3), the organization officially reversed its stance on HCQ. Now, they say its potential for good currently may supersede the threat of any potentially harmful side effects"

What I found:

https://factcheck.afp.com/us-medical...19-treatment-0

[WillBrink]

Double tap. But, some studies of possible interest:

Meltzer DO, et al. Association of vitamin D status and other clinical characteristics with COVID-19 test results. JAMA Network Open. 2020; doi:10.1001/jamanetworkopen.2020.19722.
Carpagnano GE, et al. Vitamin D deficiency as a predictor of poor prognosis in patients with acute respiratory failure due to COVID-19. Journal of Endocrinological Investigation. 2020; doi:10.1007/s40618-020-01370-x.
Castillo ME, et al. Effect of calcifediol treatment and best available therapy versus best available therapy on intensive care unit admission and mortality among patients hospitalized for COVID-19: A pilot randomized clinical study. The Journal of Steroid Biochemistry and Molecular Biology. 2020; doi:10.1016/j.jsbmb.2020.105751.
Bergman P. The link between vitamin D and COVID-19: Distinguishing facts from fiction. Journal of Internal Medicine. 2020; doi:10.1111/joim.13158.
Vitamin D. National Institutes of Health. https://www.covid19treatmentguidelin...apy/vitamin-d/. Accessed Sept. 9, 2022.

[Arik]

And yet crickets from the "follow the science" crowd

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[WillBrink]

And yet crickets from the "follow the science" crowd

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Cognitive dissonance is a thing, even among the sci/med community. The debate often comes down to whether there's enough data to warrant use of X, but I do find there's often a double standard as to level of evidence expected/accepted.

[WillBrink]

Forum is glitching again.

[WillBrink]

Page does a nice meta analysis of D and covid. However, it's not peer reviewed J published, so keep that aspect in mind:

https://vdmeta.com/

[The Dumb Gun Collector]

What causes these Vitamin D deficiencies? Just lack of sun? Skin tone?

[Arik]

What causes these Vitamin D deficiencies? Just lack of sun? Skin tone?

My understanding is diet and sunlight but mostly sunlight.

Western diet is lacking in Vitamin D. You don't hear too many people eating Okra, Kale, Sardines, Salmon, cod liver, organ meats on a weekly basis


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