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Thread: Covid 19 Sci/med discussions only

  1. #301
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    Interesting.

    https://www.skynews.com.au/details/_6158843835001

    Coronavirus may have been a 'cell-culture experiment' gone wrong
    Sharri Markson|24/05/2020|16min
    EXCLUSIVE: The coronavirus that has become a world-wide pandemic may have been created in a “cell-culture experiment” in a laboratory, according to prominent scientists who have conducted ground-breaking research into the origins of the virus. Flinders University Professor Nikolai Petrovsky has completed a scientific study, currently undergoing peer review, in conjunction with La Trobe University in Victoria, which found COVID-19 was uniquely adapted for transmission to humans, far more than any other animal, including bats. Professor Petrovsky, from the College of Medicine and Public Health at Flinders University who has spent the past 20 years developing vaccines against pandemic influenza, Ebola and animal SARS, said this highly unusual finding left open the possibility that the virus leaked from a laboratory.

    (Excerpt)

  2. #302
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    Study in process in progress hopefully. Results will be interesting, especially being it’s looking at prevention:

    A Study of Hydroxychloroquine, Vitamin C, Vitamin D, and Zinc for the Prevention of COVID-19 Infection (HELPCOVID-19)
    Detailed Description:

    In this study, subjects will take a regimen of hydroxychloroquine, vitamin C, vitamin D, and Zinc to test if this combination can prevent COVID-19. Treatment with hydroxychlorquine will last 1 day. Treatment with vitamin C, vitamin D, and and zinc will last 12 weeks. The study will last 12 weeks.

    https://clinicaltrials.gov/ct2/show/NCT04335084
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  3. #303
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    [mention]WillBrink [/mention] i would be really interested in a study of significantly ill and dead and their max VO2. Since Covid already seems to target weak respiratory and circulatory systems and Max VO2 really is a measure of those two systems, it makes sense to my non-biologist mind.

    Current Apple watches combined with an iPhone will give an estimated max VO2 already, so the data might be unexpectedly be available...

  4. #304
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    Quote Originally Posted by sandsunsurf View Post
    [mention]WillBrink [/mention] i would be really interested in a study of significantly ill and dead and their max VO2. Since Covid already seems to target weak respiratory and circulatory systems and Max VO2 really is a measure of those two systems, it makes sense to my non-biologist mind.

    Current Apple watches combined with an iPhone will give an estimated max VO2 already, so the data might be unexpectedly be available...
    Via testing pulse ox, radiograph imagining, and other methods, they have a good handle on lung capacity and function of those with covid. A major disconnect and debate, much of which posted in this thread, has been whether intubating people causes more harm than good in many if not most with covid, who show conflicting indicators of lung function with covid. The term given is "happy hypoxia."

    The mystery of the pandemic's ‘happy hypoxia’

    https://science.sciencemag.org/content/368/6490/455
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  5. #305
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    I actually remember reading that article and didn’t make the connection of blood clots. Which may lean towards meaning that a high max VO2 doesn’t matter.

    I still think that it would be nice to see a study of respiratory and cardiovascular health vs negative outcome with covid infection.

  6. #306
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    Quote Originally Posted by sandsunsurf View Post
    I actually remember reading that article and didn’t make the connection of blood clots. Which may lean towards meaning that a high max VO2 doesn’t matter.

    I still think that it would be nice to see a study of respiratory and cardiovascular health vs negative outcome with covid infection.
    The essential co morbidities are known, but you could also make the leap that those with good respiratory and cardiovascular health are in generally better health and less likely to experience serious complications from Covid. I don't think that's an unreasonable correlation to make.
    - Will

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  7. #307
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    This is interesting

    https://www.rt.com/news/490828-lance...n-coronavirus/

    "The Lancet, one of the top medical journals in the world, has retracted a study questioning the safety of treating Covid-19 with anti-malaria drug hydroxychloroquine, following controversy surrounding the research firm behind it.

    The retraction officially came at the request of the study’s authors, who admitted on Thursday they could “no longer vouch for the veracity of the primary data sources.”

    "We deeply apologize to you, the editors and the journal readership for any embarrassment or inconvenience that this may have caused,” the authors added.

    The data used in the study appeared to show that chloroquine and hydroxychloroquine caused higher death rates in test subjects. It was cited far and wide as grounds to halt testing of both drugs in Covid-19 patients, including by the World Health Organization.

    Healthcare analytics firm Surgisphere, which provided the data, has come under serious scrutiny in recent days as details about the company have come to light.

    Though the firm claimed to have gathered their data from thousands of patients at hundreds of hospitals worldwide, an independent investigation has questioned the accuracy of their research. The firm was also found to have almost no online presence and only a handful of employees, one of whom is a science fiction writer and another who is an “adult” entertainer.
    Last edited by Arik; 06-04-20 at 18:02.

  8. #308
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    I guess we're not worried about CV-19 anymore...

    Gettin' down innagrass.
    Let's Go Brandon!

  9. #309
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    https://www.cnbc.com/amp/2020/06/08/...-who-says.html

    So now asymptomatic spread is very rare. Well that’s certainly some good news.

  10. #310
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    Quote Originally Posted by Life's a Hillary View Post
    https://www.cnbc.com/amp/2020/06/08/...-who-says.html

    So now asymptomatic spread is very rare. Well that’s certainly some good news.
    The issue with the news conference is the WHO was making a huge deal out of the differences between asymptomatic and pre-symptomatic cases, and applying them in a way that's counterintuitive for everyone that isn't studying that data set.

    https://arstechnica.com/science/2020...at-they-meant/

    From the comments section "It’s one thing for technical terms to have a specific technical meaning - every domain has words like that. And for words that are complex and nuanced that’s normal and not likely to lead to trouble. But when your technical definition runs diametrically counter to an obvious and clear layman’s understanding of the word... it’s time to revise your technical terminology.

    Asymptomatic transmission is a totally clear word. All it’s parts are clear. Asymptomatic = without symptoms. Transmission = well... transmission. Just about any normal person seeing those two words put together would assume they meant “transmission by someone who isn’t symptomatic at the time.” To give it a more restrictive unintuitive technical definition is just an all around fail. Especially since the definition they’re using isn’t even widely accepted in the field!

    As an epidemiologist previously working in malaria prevention (where there is a ton of asymptomatic transmission by any definition of the word) we define asymptomatic transmission just like you would expect - “asymptomatic at the time of transmission”. Then we break that down into 2 cohorts - asymptomatic transmission in pre-symptomatic individuals and asymptomatic transmission in individuals who never become symptomatic. Why WHO needed to reinvent the wheel to make it more confusing is beyond me!"


    So ok news, but poor communication skills.

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