Covid 19 Sci/med discussions only

[jbjh]

Dade county Florida just reported a stunning 33% positive testing rate. In contrast, New York is having difficulty finding even a 1% positive rate, and New Jersey is close to the same. I'm sure some would like to attribute it to the leadership of Cuomo and Murphy, but I think it has more to do with COVID having already ripped though NY/NJ resulting in increased effects of herd immunity, while other states that had not been hit hard are now getting it.

From everything I’ve read, nowhere is close to herd immunity. A new study from Spain (who were the other hotspot after Italy) paints a grim picture

https://www.bioworld.com/articles/43...d-unachievable

“Overall, roughly 5% of the population had antibodies to the virus, Antibody prevalence was higher in hotspot areas, but was no higher than 15% even in heavily affected regions.”



Sent from 80ms in the future

[WillBrink]

The model I proposed in March via my article on potential approaches to life threatening complications from Covid was:

Oxidative stress -> formation of ROS -> cytokine storm -> sepsis, ARDs, and related sequela of Covid-19.

I have recently updated this article with new data and resources following this paper below discussed below.

It's interesting and important to note the role of Oxidative stress is starting to be recognized, yet they're still not making the obvious leap to addressing the cause of the hyper immune response (OS -> immune response) vs the inflammation aspects of that response. That is, clinically they're still attempting to address it as the inflammatory stage, vs addressing it at the Oxidative stress (OS) phase.

This is a recent paper on the role of Oxidative stress and covid complications, yet still fails to mention the use of key anti oxidants for treatment options as the obvious way of addressing the OS and potentially mitigating the hyper inflammatory response. I think that could be a worthy paper if someone wanted to follow up on that, and my article linked below has additional resources:

Archives of Medical Research
Volume 51, Issue 5, July 2020, Pages 384-387
Archives of Medical Research
Review Article

Oxidative Stress as Key Player in Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) Infection

The emergence of viral respiratory pathogens with pandemic potential, such as severe acute respiratory syndrome coronavirus (SARS-CoV), the pathogenic agent of Covid-19, represent a serious health problem worldwide. Respiratory viral infections are, in general, associated with cytokine production, inflammation, cell death, and other pathophysiological processes, which could be link with a redox imbalance or oxidative stress. These phenomena are substantially increased during aging. Actually, severity and mortality risk of SARS-CoV-2 infection or Covid-19 disease have been associated with the age. The aim of the present work was to contribute with the understanding of the possible link between oxidative stress and the pathogenesis, severity and mortality risk in patients affected by SARS-CoV infection.

Full paper:

https://www.sciencedirect.com/scienc...88440920305403

Updated article:

https://brinkzone.com/life-saving-st...complications/

[WillBrink]

From everything I’ve read, nowhere is close to herd immunity. A new study from Spain (who were the other hotspot after Italy) paints a grim picture

https://www.bioworld.com/articles/43...d-unachievable

“Overall, roughly 5% of the population had antibodies to the virus, Antibody prevalence was higher in hotspot areas, but was no higher than 15% even in heavily affected regions.”



Sent from 80ms in the future

I tend to think that's a problem with the accuracy of the tests vs the % of people who have been exposed, but we will not know for some time.

[Grand58742]

I think we're moving closer and closer to cancelling fall collegiate sports on a broad scale this year. The Big 10 and Pac-12 have already cancelled out of conference games (which theoretically could push the start back if they reschedule the current games) and several smaller leagues have cancelled them outright moving to the spring.

It'll either be delayed to a later start in October or moved outright to the spring.

[ChattanoogaPhil]

Governor DeSantis stated the other day that near 40% of those admitted to Miami-Dade hospitals for non-COVID related treatment, everything from auto accidents to birthing, are testing positive and asymptomatic. Statewide, positives are running close to 20%.

Meanwhile... where COVID has already ripped through the state of New York, positives are running under 1%, and I believe they reported zero deaths yesterday.

[Whiskey_Bravo]

Governor DeSantis stated the other day that near 40% of those admitted to Miami-Dade hospitals for non-COVID related treatment, everything from auto accidents to birthing, are testing positive and asymptomatic. Statewide, positives are running close to 20%.

Meanwhile... where COVID has already ripped through the state of New York, positives are running under 1%, and I believe they reported zero deaths yesterday.

The system my wife works at is testing everyone that comes into the hospital no matter the reason. Many of their positive test are resulting from that. Come in for a broken arm you get tested.

[odugrad]

The system my wife works at is testing everyone that comes into the hospital no matter the reason. Many of their positive test are resulting from that. Come in for a broken arm you get tested.

And from what I'm hearing those are all being counted as covid-19 hospitalizations.

[ChattanoogaPhil]

The system my wife works at is testing everyone that comes into the hospital no matter the reason. Many of their positive test are resulting from that. Come in for a broken arm you get tested.

Right. Below is a Texas hospital CEO explaining the same thing.

In addition, they are all listed as a "COVID hospitalizations". Come in asymptomatic to get a broken finger looked at, test positive, get logged in as a COVID hospitalization then leave 30 minutes later.

-----

Excerpts

Texas hospital CEO: COVID inpatient count 'misinterpreted,' level of alarm 'unwarranted'

Health officials in Texas are logging every single COVID-19-positive hospital patient in the state as a COVID-19 hospitalization, even if the patients themselves are admitted seeking treatment for something other than the coronavirus.

The number of hospitalizations are "being misinterpreted," said Houston Methodist CEO Marc Boom, "and, quite frankly, we’re concerned that there is a level of alarm in the community that is unwarranted right now."

https://justthenews.com/politics-pol...-hospital-case

[Life's a Hillary]

And from what I'm hearing those are all being counted as covid-19 hospitalizations.

They are but the problem is they all have to use the same precautions as someone who comes into the hospital for COVID symptoms and is positive. It creates a lack of space and doctors. Say you get in a car wreck and have to be admitted and you pop positive. You can’t just sit in a normal hospital bed and be seen by any doctor/nurse. You have to go into the COVID wing that is specially designed or converted to hold COVID patients and you only see doctors working those shifts. You can get a specialist to look at your chart but if they are not working with COVID patients then chances are they will not evaluate in person.

It might create a false perception of how hard the disease is hitting people but they still require a special hospital bed and team of medical practitioners which causes more complications for the hospital. Also, some specialists are being called in to work with COVID patients and this limits their availability to treat other patients. Not to mention instances where “non-emergency” medical procedures are being put on hold which is going to create major health issues down the road.

[chuckman]

The system my wife works at is testing everyone that comes into the hospital no matter the reason. Many of their positive test are resulting from that. Come in for a broken arm you get tested.

And from what I'm hearing those are all being counted as covid-19 hospitalizations.

Right. Below is a Texas hospital CEO explaining the same thing.

In addition, they are all listed as a "COVID hospitalizations". Come in asymptomatic to get a broken finger looked at, test positive, get logged in as a COVID hospitalization then leave 30 minutes later.

-----

Excerpts

Texas hospital CEO: COVID inpatient count 'misinterpreted,' level of alarm 'unwarranted'

Health officials in Texas are logging every single COVID-19-positive hospital patient in the state as a COVID-19 hospitalization, even if the patients themselves are admitted seeking treatment for something other than the coronavirus.

The number of hospitalizations are "being misinterpreted," said Houston Methodist CEO Marc Boom, "and, quite frankly, we’re concerned that there is a level of alarm in the community that is unwarranted right now."

https://justthenews.com/politics-pol...-hospital-case

Everyone coming into our hospital as an admit is getting tested, but we are only classifying it a COVID admission if they are being admitted for COVID. Otherwise it's a secondary diagnosis. Where things get goofy is, say, you are being admitted for broken arm, and you test positive for COVID. After you go to the OR to have your arm fixed you become symptomatic with COVID. How does that change reportable numbers? Everywhere struggles with that.

The numbers are a shell game, and while a lot of people are hurling the "everyone is lying" accusation because the numbers seem to always change, and I do know that is occurring, it's also much more complex.