Originally Posted by
chuckman
That wasn't what I said; at least, not what I had implied. I try to be neutral given that I am not an ordering provider. I get leery of claims of 'wonder drugs' when we've seen a) it can become politicized or monetized, and b) a lot of 'wonder drugs' end up being bad (i.e., phen-phen). I also try to apply by own analysis in my context of what I have seen work and not work.
I think one reason we see metformin so popular is that it's been around for a while, it's cheap, and it has a known safety profile. I do doubt we'll see it go very far off-formulary for a lot of things. We are seeing clinically something called the 'COVID effect': providers NOT ordering meds so as to not be cast in the same light as ivermectin, etc. I am also seeing it prescribed less now in favor of SGLT2 meds, but a lot remains to be seen how those pan out over time.
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