A slight, almost negligible, but in rare cases applicable point would be how much FOV the tube itself occludes - would mostly involve the firing side peripheral vision, and the crescent hidded by the tube.
With my primary optic all the way back, I have a slight amount covered up that isn't seen by my non-dominant eye.
So, I would want to move it forward until that area hidden by the tube is covered by my other eye, which only requires an inch or so of movement for the optic. For a non-NTCH shooter, this is much less noticeable.
I end up with a compromise - most of the way forward on the receiver, because it helps with some of these advantages, but doesn't give me a tiny blind spot that I dislike, and is a rough middle ground between the far-forward easy to acquire dots, and more weight-practical rear mounting options.
I think this reason is why the front 1/3 of the receiver are most commonly used rail slots.
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Semper Fi
"Being able to do the basics, on demand, takes practice. " - Sinister
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