Well the bolt is different for sure but a 5.56 extractor will work in a S&W 5.45 upper. At least that has been my experience and many others as well.
The thing is that a 5.56 extractor will cost about $10-$15. According to another member here, they go for $40 from S&W directly. Which is a huge difference. My original extractor broke at about 1k rounds and S&W said I had to ship out the whole upper and the wait time could be from 3-5 weeks!
So I did a bit of reading and ordered a 5.56 extractor. I thought if it doesn't work I still have other 5.56 uppers I could use it as a spare. But once installed it worked great!
Took a couple of rounds to get broken in because the first few rounds would fail to eject but once it was, it was smooth sailing.
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