Well, when you look at the shear numbers*, the fact that just about every where we look we are finding planets outside our solar system (it was never known if planets were common or rare, it's now clear planets are very common with new planets being found almost weekly now) the fact that life is not nearly as rare/delicate as once thought, etc, etc, I think it statistically unlikely we are all there is in the universe for intelligent life forms. But as you say, until proven otherwise, it's a WAG at this point.
* = Not sure if this the very least numbers, but there are between 200 - 400 billion stars in our galaxy alone. There are possibly 100 billion galaxies + in the observable Universe. So, that's (conservatively) 100 billion X 200 -400 billion stars, many (most?) of which have planets around them.



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